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e visit m.fema.gov. <a href=http://airmax.esc24.net>cheap nike air max</a> LONDON ï¿½ Pharmaceutical company AstraZeneca on Friday flatly rejected drug maker Pfizer's sweetened takeover bid ï¿½ worth $106 billion ï¿½ just hours after it was levelled, describing it as inadequate.After being rebuffed twice, Pfizer Inc., the maker of Viagra, made a third attempt for the London-based rival on Friday, offering 50 pounds ($84) a share in cash and stock, a 7.3 increase on its last bid. The deal would be the biggest-ever foreign takeover of a British business.But AstraZeneca's board said the terms were not right and the price substantially undervalued the company. The Anglo-Swedish firm said the potentially lucrative "pipeline" of new drugs it is developing would be disrupted by a takeover and its possible consequences."Pfizer's proposal would dramatically dilute AstraZeneca shareholders' exposure to our unique pipeline and would create risks around its delivery," said Leif Johansson, the chairman of AstraZeneca. "As such, the board has no hesitation in rejecting the proposal."ï¿½Pfizer's bid early Friday comes amid a spate of mergers and acquisitions in the pharmaceutical industry, which is moving to consolidate gains as the patents on some top earners expire. Besides getting access to a pipeline with promising assets, particularly in immuno-oncology, analysts suggest that the deal gives Pfizer tax advantages."There is a highly compelling strategic, business and financial rationale for combining our businesses, with significant benefits for shareholders and stakeholders of both companies," Pfizer CEO Ian Read said in a statement announcing the offer.But the move quickly became political in Britain. Critics fear the takeover could mean big job cuts, and the potential loss of stature in the country's science sector.Cognizant of the concerns, Pfizer sent a letter to Prime Minister David Cameron, promising to keep the company's corporate and tax residence in England. It said that the "golden triangle of Oxford, Cambridge and London" ï¿½ where a significant portion of British scientific research is based ï¿½ would represent a vital component of the deal.Cameron responded within a few hours, declaring that while the government regards the potential takeover bid as a matter for the respective boards, the government was "determined to secure great British science, research and manufacturing jobs in the life sciences sector.""The government will consider these proposals carefully as to whether they offer sufficient protection of our priorities," Cameron said.Britain is investing millions of pounds into boosting science in the so-called "Golden Triangle" in the country's southeast. Only last month, London Mayor Boris Johnson announced a new investment organization meant to attract life sciences corporations and to facilitate collaboration between companies and researchers.Besides access to the intellectual capital, some analysts say the main impetus for Pfizer's interest in AstraZeneca is a wish to limit a potential tax hit. They suggest Pfizer has earned and held billions of cash overseas that it would have to pay taxes on at relatively high U.S. rates should it be brought back.Page 2 of 2 - "Once the cash is offshore, the potential tax cost of repatriating it to the U.S. makes it much more attractive to find other homes for it ï¿½ such as making foreign acquisitions," said tax specialist Heather Self of the law firm, Pinsent Masons.Other observers, like Alex Arfaei, the pharmaceutical analyst for BMO Capital Markets in Toronto, said that regardless of whether Pfizer may be doing this from a position of strength or weakness, the deal represents a unique opportunity."It allows Pfizer not only to significantly lower its taxes ... but also to optimize its vast commercial infrastructure following the loss of exclusivity of some big blockbusters like Celebrex and significantly boost its pipeline with some very promising assets, particularly in immuno-oncology," he wrote.Pfizer is the world's second-biggest drugmaker by revenue, with sales of $51.6 billion last year and staff of 77,700. AstraZeneca PLC ranks eighth, with sales of $25.7 billion last year and 51,500 employees worldwide. AstraZeneca was created in 1999 through the merger of Sweden's Astra and Britain's Zeneca.Paul Nurse, the president of the Royal Society, said that whatever the outcome of the takeover bid, it remains vital to the U.K. economy to invest in research."Sadly, too much of the focus of this debate has been on current share values, tax breaks and the short term profits that can be made on the deal," Nurse said. "This is exactly the sort of 'get rich quick' culture that brought the global economy to its knees a few years ago."
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In old business, council members adopted an ordinance to ask voters to extend aldermen's terms to four years for the purpose of staggering council members' terms. The question will be placed on the November general election ballot. If approved, the extension will go into effect in the 2016 general election with each alderman in Ward 1 seeking four year terms and aldermen in Ward 2 elected to two year terms. Beginning in 2018, all aldermen would seek four year terms.In other business, council members approved the mayor's recommendation to appoint Jimmy Jeffress to the library board and Ronnie King to the Crossett Port Authority Board. Alderwoman Candace Jeffress withdrew from the meeting room in voting for the appointment for Jeffress. The council also approved a request by Howard Beatty, chairperson of the beautification committee, to designate May 31 as a city wide clean up day and June 7 as an alternate date in case of rain.Gayle Zimmerman again approached the council and requested the city enforce zoning ordinances regarding neighboring property owned by Fernando Mondragon. Zimmerman previously approached the council and alleged that Mondragon is operating a lawn care business out of his home and that it is in violation of the city's zoning ordinances.Following a detailed discussion, council members followed the recommendation of city engineer Jeff Harrison that Mondragon is not in violation of the city's zoning ordinances. Although Mondragon stores equipment on the properties, he does not conduct his lawn care service at the property, said Harrison.During Monday's meeting, Zimmerman stated, <the>Mondragons] live two doors down from me, and they are running a business out of their home. Zimmerman stated while she was sitting on her porch drinking coffee Easter Sunday morning, she was disturbed by the sound of Mondragon driving his tractor at one of the neighboring properties. She alleged that the noise created by the equipment and odors violate the city's zoning ordinances and stated that if the council chooses not to enforce its ordinances that she will consider taking the matter to litigation. In response to Zimmerman's statements, City Attorney James Hamilton stated it is his opinion that the city is not violating any ordinances. <a href=http://louboutin.tourneurbois.fr>louboutin</a> With more and more shows getting cancelled and uncanceled ("The Killing" has been canceled twice but will finish out a fourth and final season on Netflix, along with the recently uncanceled "Arrested Development"), it was only a matter of time before Jack Bauer returned to the screen. After an aborted attempt at a feature film, stars Kiefer Sutherland and Mary Lynn Rajskub (as computer-programmer sidekick Chloe) return to television in a 12-episode summer event. With many of the same writers and producers, and still using the real-time format that made the series unique, Fox is banking on Sutherland's continued appeal to bring big ratings to its summer schedule. Family audiences can expect similar content to the previous series, which had very occasional language and a rather high amount of action and war-related violence. <a href=http://longchamp.tourneurbois.fr>longchamp soldes</a>
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